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OSD-172 · GLDS-172

Dynamic gene expression response to altered gravity in human T cells (parabolic flight)

Study overview

What the record says

We investigated differentially regulated genes in human Jurkat T lymphocytic cells in 20s and 5min microgravity and in hypergravity and compared expression profiles to identify potential gravity-regulated genes and adaptation processes. This dataset is part of a series of three, and the other two datasets are deposited in GLDS-188 and GLDS-189.

Structured metadata

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01

Biological subject

Organism
Homo sapiens
Material
Cells

02

Measurement

Measures
transcription profiling
Platform
Affymetrix

03

Experimental factors

Factor type
Gravity Altered
Factor name
Altered Gravity

04

Mission context

Flight program
Airbus A300 ZERO-G
Space program
German Aerospace Center (DLR)

People & publication

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Publication
Dynamic gene expression response to altered gravity in human T cells Stability of gene expression in human T cells in different gravity environments is clustered in chromosomal region 11p15.4
Investigators
Cora S. Thiel