OSD-188 · GLDS-188
Dynamic gene expression response to altered gravity in human T cells (sounding rocket flight)
Study overview
What the record says
We investigated differentially regulated genes in human Jurkat T lymphocytic cells in 20s and 5min microgravity and in hypergravity and compared expression profiles to identify potential gravity-regulated genes and adaptation processes. This dataset is part of a series of three, and the other two datasets are deposited in GLDS-172 and GLDS-189.
Structured metadata
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01
Biological subject
- Organism
- Homo sapiens
- Material
- Cells
02
Measurement
- Assay
- DNA microarray
- Measures
- transcription profiling
- Platform
- Affymetrix
03
Experimental factors
- Factor name
- Altered Gravity
04
Mission context
- Space program
- German Aerospace Center (DLR)
People & publication
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- Publication
- Dynamic gene expression response to altered gravity in human T cells Stability of gene expression in human T cells in different gravity environments is clustered in chromosomal region 11p15.4 Expression of Hypoxia-Inducible Factor 1α (HIF-1α) and Genes of Related Pathways in Altered Gravity Transcriptional Homeostasis of Oxidative Stress-Related Pathways in Altered Gravity
- Investigators
- Cora S Thiel